Molecular Library

Look up the science behind every challenge.

DNA

Deoxyribonucleic acid — the double-helix molecule that stores genetic information using bases A, T, C, G.

Two antiparallel strands held together by complementary base pairs: A–T and C–G. Each strand is a template for replication.

RNA

Ribonucleic acid — a single-stranded copy of genetic information that uses Uracil (U) instead of Thymine (T).

Messenger RNA (mRNA) carries instructions from DNA to the ribosome. Transcription pairing: A→U, T→A, C→G, G→C.

Base Pairing

The rules that keep the genetic code accurate.

DNA: A–T, C–G. RNA complement: A–U, C–G. These rules make replication and transcription reliable.

Replication

Copying DNA before cell division.

Strands separate, complementary nucleotides are added to each template, and two identical double helices form.

Transcription

Making mRNA from a DNA template.

RNA polymerase reads the template strand and builds complementary mRNA, which then leaves the nucleus.

Translation

Building a protein from mRNA.

Ribosomes read mRNA in codons (groups of 3). tRNA brings matching amino acids until a stop codon ends the chain.

Codon & Anticodon

Three-base units that specify amino acids.

A codon on mRNA pairs with a complementary tRNA anticodon. AUG is the start codon; UAA, UAG, UGA are stop codons.

Mitosis

Nuclear division that produces two identical diploid cells for growth and repair.

Phases: prophase, metaphase, anaphase, telophase, then cytokinesis. Chromosome number stays 2n → 2n.

Meiosis

Two divisions that produce haploid gametes with genetic diversity.

Homologs pair and may cross over in Prophase I. Meiosis I reduces 2n → n; Meiosis II separates sister chromatids.

Mendelian Inheritance

How alleles pass from parents to offspring.

Genotype is the allele pair; phenotype is the trait. Dominant alleles mask recessive ones in heterozygotes. Punnett squares predict ratios.

Mutation

A change in DNA sequence that can alter proteins or stay silent.

Substitutions, insertions, and deletions create variation. Repair systems catch many errors; remaining changes feed evolution and sometimes disease.

Evolution

Change in allele frequencies in a population over generations.

Mutation and recombination create variation; natural selection, drift, and gene flow change which alleles become common.